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(B) The likelihood that nonusers of tobacco products and solutions who undertake the tobacco product or service will change to other tobacco products that may perhaps present larger amounts of individual health risk; and
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Historically, from your 1970s, the tobacco market has performed pharmacological research on several nicotine analogs, to understand their pharmacological consequences and ascertain their prospective to replace nicotine in goods and also to bypass any foreseeable laws on nicotine14. Before receptor binding and rodent scientific studies have demonstrated that, compared to nicotine, various methylated nicotine analogs, like 6MN, have differential pharmacological, behavioral, and toxicological effects.
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(A) Facts describing how the container closure procedure guards and preserves the product or service from injury in the course of transportation, environmental contaminants, and possible leaching and migration of packaging constituents to the new tobacco item; and